Lassie and 12-year-old Florien are inseparable best friends, so it breaks both their hearts when Lassie is sent away after Florien's father loses his job. While Lassie's temporary minders, which includes 12-year-old Priscilla, mean well; Lassie is mistreated by an opportunist caretaker and escapes the first chance she gets. It is the start of an epic adventure across southern Germany as Lassie makes her way back home while Florien and Priscilla set out to find her.