Abel (The Weeknd), a musician plagued by insomnia, meets Anima (Jenna Ortega), a troubled young woman who has similar struggles with loneliness and abandonment. They run away together, but when he decides to return to complete his world tour without Anima, she knocks Abel out and ties him up.

His manager Lee (Barry Keoghan) shows up to free Abel from Anima and help get him back on tour.